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Cardiovascular Pathology

0All Topics46 questions
1Arteriosclerosis and Atherosclerosis5 questions
2Vasculitis0 questions
3Tumours of the Blood Vessels0 questions
4Congenital Heart Disease1 questions
5Valvular Heart Disease6 questions
6Ischaemic Heart Disease6 questions
7Hypertensive Heart Disease6 questions
8Cardiomyopathy0 questions
9Myocarditis0 questions
10Pericardial Disease0 questions
11Cardiac Tumours0 questions
MCQsSAQsLEQs

Ischaemic Heart Disease ยท0/0 correct0 correct / 0 attempted / 6 total

Back to Cardiovascular Pathology

A 58-year-old man presents with 2 hours of central crushing chest pain radiating to the left arm. Troponin is significantly elevated. Which of the following best describes the earliest microscopic change seen in irreversibly injured myocardium after infarction?

ACoagulative necrosis with preserved cell outlines
BDense scar tissue replacing the myocardium
CNeutrophilic infiltration only, with no cell death
DGranulation tissue with new capillary formation

Which of the following is the single most important modifiable risk factor for the development of ischaemic heart disease?

AFamily history of premature coronary artery disease
BCigarette smoking
CMale sex
DAdvancing age

A patient develops sudden hypotension and distended neck veins 5 days after a transmural anterior myocardial infarction. Echocardiography shows a large pericardial effusion with tamponade physiology. Which complication has most likely occurred?

APapillary muscle rupture
BVentricular free wall rupture
CVentricular septal rupture
DDressler syndrome

Stable angina pectoris is classically produced by fixed coronary artery stenosis of what approximate luminal narrowing?

AGreater than 75%
BGreater than 25%
CGreater than 50%, always symptomatic at rest
DComplete (100%) occlusion

Which cardiac biomarker remains the most sensitive and specific for detecting myocardial injury, and can stay elevated for up to 7-10 days after infarction?

ACreatine kinase-MB (CK-MB)
BCardiac troponin
CMyoglobin
DLactate dehydrogenase (LDH)

Which of the following IS NOT an acute plaque change implicated in the pathogenesis of myocardial infarction?

AFibrosis and aneurysm
BRupture/fissuring
CErosion/ulceration
DHemorrhage